In 2012 I completed my DPhil (PhD) studies in Molecular Genetics in the Department of Biochemistry, University of Oxford.
During this time I investigated genetic mechanisms regulating chronological and replicative ageing in the budding yeast Saccharomyces cerevisiae using several approaches from biochemistry, molecular biology, microscopy, and bioinformatics.
The final version of my thesis is available for download here. The thesis has a record in the British Library EThOS and the Oxford University Research Archive.
Please cite as:
Ayling, Jonathan. 2012. “Epigenetic Regulation of Chronological and Replicative Longevity in Saccharomyces Cerevisiae.” PhD thesis, University of Oxford.
I also published a paper in Nucleic Acids Research –
Murray SC, Serra Barros A, Brown DA, Dudek P, Ayling J, Mellor J. A pre-initiation complex at the 3'-end of genes drives antisense transcription independent of divergent sense transcription. Nucleic Acids Res. 2012 Mar;40(6):2432-44
Epigenetic Regulation of Chronological and Replicative Longevity in Saccharomyces Cerevisiae is © Jonathan Ayling (2012).